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Alcohol-Associated Liver Disease

By October 23rd, 2025No Comments6 min read

In this video, consultant hepatologist Mark Wright explains liver disease and how not drinking alcohol can help. Even if you have been a heavy drinker for many years, reducing or stopping your alcohol intake will have important short-term and long-term benefits for your liver and overall health. Those who regularly drink more than the recommended daily limits of alcohol should not stop drinking without medical support.

Abstinence

If you regularly drink alcohol to excess, tell your GP so they can check if your liver is damaged. This means ARLD is frequently diagnosed during tests for other conditions, or at a stage of advanced liver damage. Cognitive behavioral therapy (CBT) and medications called benzodiazepines can ease withdrawal symptoms in a person with alcohol dependency.

  • Alcohol misuse is now one of the most common causes of death in the UK, along with smoking and high blood pressure.
  • Alcoholic liver disease is treatable if it is caught before it causes severe damage.
  • There are 3 main stages of ARLD, although there’s often an overlap between each stage.
  • Jaundice happens when a substance called bilirubin builds up in the body.
  • In compensated cirrhosis, the liver remains functioning, and many people have no symptoms.

The liver is one of the most complex organs in the body. Send a note of thanks to Mayo Clinic researchers who are revolutionizing healthcare and improving patient outcomes. They’re often due to restricted blood flow through the portal vein. The portal vein carries blood from the intestine, pancreas and spleen to the liver.

What causes alcohol-associated liver disease?

For men, having 4 to 5 drinks a day for six months or longer raises the risk of the disease. Not everyone who drinks this much will get the Alcoholic Liver Disease disease, but the chances are much higher. The most common symptom of alcoholic hepatitis is the skin and whites of the eyes turning yellow.

Medical

Your prognosis (outlook) will depend on the stage of your liver disease and whether you stop drinking alcohol. If you’re still in the early stages, you can stop the process and reverse the damage. Steatosis — fat storage in your liver — may stop in as little as six weeks. How much and how often you drink alcohol are the most important risk factors in developing ALD. So, your risk is higher if you have alcohol use disorder or engage in routine binge drinking. Alcohol may also do more damage to your liver if you have another liver disease at the same time — like hepatitis C.

  • However, eligibility may depend on being abstinent from alcohol for a specific length of time.
  • People with both conditions are more likely to have liver failure, need to be hospitalized and have a higher risk of dying than people with alcoholic hepatitis alone.
  • Females who consume high amounts of alcohol and also carry excess body weight have a greater chance of developing chronic liver disease.
  • The main treatment is to stop drinking, preferably for the rest of your life.

Related MedlinePlus Health Topics

In decompensated cirrhosis, symptoms become more apparent. Someone with decompensated cirrhosis may develop ascites (or fluid in the abdomen), gastrointestinal bleeding, and hepatic encephalopathy, in which the brain is affected. In liver failure, the liver is severely damaged and can no longer function. Other organs, such as the kidneys, and body systems such as the respiratory system, may also begin to fail.

However, eligibility may depend on being abstinent from alcohol for a specific length of time. After stopping drinking, which is the first step in any treatment of ALD, an assessment will be made as to the extent of the damage and the overall state of the body. Treatment also consists of evaluation for other risk factors that can damage the liver or put the liver at higher risk, such as infection with hepatitis C and metabolic syndrome. However, if the person drinks alcohol again heavily, the fatty deposits will reappear.

Reducing weight if you’re overweight, eating a healthy diet, and regular exercise can help someone with early ALD who has stopped drinking decrease their risk of advanced liver disease. There are normally no symptoms, and alcoholic fatty liver disease is often reversible if the individual abstains from alcohol from this point onward. Cirrhosis is the most advanced stage of alcohol-related liver disease. It prevents the liver from working properly, and it cannot be reversed. Some people have both alcoholic hepatitis and cirrhosis at the same time.

Health Conditions

If the inflammation becomes severe enough to cause jaundice, and in some cases acute liver failure, the condition is called alcoholic hepatitis. As alcoholic hepatitis progresses, liver cells can die, bile can build up, and healthy tissue can be replaced by scar tissue, a condition called fibrosis in the early stages. Scarring may become more severe over time, leading to cirrhosis.

However, in advanced alcoholic liver disease, liver regeneration is impaired, resulting in permanent damage to the liver. Once a doctor diagnoses a person with alcoholic liver disease at any stage, they will recommend them to never resume drinking. Any conditions that have reversed will typically return once drinking restarts.

The early signs of alcoholic liver disease are vague and affect a range of systems in the body. Alcoholic liver disease is liver damage from overconsuming alcohol. It can cause a buildup of fats, inflammation, and scarring.

Individuals should seek help from a medical professional to safely manage alcohol withdrawal. When liver cells are damaged, the body’s immune system tries to help, but this response can cause even more inflammation and damage. Alcohol also weakens the gut lining, allowing bacteria and their toxins to enter the liver from the digestive tract.

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